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About Prevenar 20™ at a Glance Serotype Coverage Pneumococcal Disease Clinical Programme RecommendationsPractical Use Resources
Recommended by [Local body] for routine vaccination1,2Complete all 4 doses on time to help babies build an optimal Prevenar 20™ (Pneumococcal 20-valent Conjugate Vaccine) immune response1,2*†‡

[Local body] recommends Prevenar 20™ for routine infant vaccination using a 4-dose schedule to reduce morbidity and other serious consequences from invasive pneumococcal disease (IPD) under 2 years of age.2

Prevenar 20™ can be coadministered with the [Local body]-recommended infant immunisation schedule.1,2
Example Text
The first dose may be given as early as 6 weeks of age.1The recommended dosing interval for the first, second, and third doses is at least 4 weeks.1The booster dose should be administered at approximately 11 to 15 months of age.1

Each dose of Prevenar 20™ is 0.5 mL.1

The United States Advisory Committee on Immunization Practices (ACIP) recommends transitioning babies to Prevenar 20™ at any point of a series started with Prevenar 13®2Catchup dosing induces immune responses to the additional serotypes covered by Prevenar 20™1,3,4Children 7 months to less than 18 years of age not yet vaccinated with Prevenar 13®

Unvaccinated patients

Children 15 months to less than 18 years of age previously immunised with Prevenar 13®

Previously immunised patients

Prevenar 20™ offers the broadest pneumococcal conjugate vaccine (PCV) serotype coverage, helping to protect preterm infants, who are at higher risk for pneumococcal disease, against the 20 serotypes in the vaccine.1,3-5Preterm infants

[Local body] recommends vaccination with Prevenar 20™ for preterm infants1,2

Children with underlying health conditions

Prevenar 20™ offers the broadest PCV serotype coverage for groups at higher risk for pneumococcal disease1-4

[Local body] recommends vaccination with Prevenar 20™ for children with underlying health conditions, including sickle cell disease and HIV1,2

Other conditions include2:

  • Cerebrospinal fluid leak
  • Chronic heart disease
  • Chronic kidney disease
  • Chronic liver disease
  • Chronic lung disease (including moderate persistent or severe persistent asthma)
  • Cochlear implant
  • Diabetes mellitus
  • Immunocompromising conditions (on maintenance dialysis or with nephrotic syndrome; congenital or acquired asplenia or splenic dysfunction; congenital or acquired immunodeficiencies; diseases and conditions treated with immunosuppressive drugs or radiation therapy, including malignant neoplasms, leukemias, lymphomas, Hodgkin disease, and solid organ transplant; HIV infection; and sickle cell disease or other hemoglobinopathies)
Given at least 8 weeks after last PCV doseHIV=human immunodeficiency virus.
Babies who have undergone haematopoietic stem cell transplant (HSCT)

[Local body] recommends vaccination with Prevenar 20™ for babies who have undergone HSCT1,2

Prevenar|| vaccines have been used to vaccinate nearly 300 million babies, including those who are preterm, have underlying health conditions, or are immunocompromised.1,2,6
Prevenar includes Prevenar® (Pneumococcal 7-valent Conjugate Vaccine) and Prevenar 13®. In [Country], Prevenar® (PCV7) was available from 2001 to 2010, and Prevenar 13® has been available since 2010.3,7,8 Access details for using and ordering Prevenar 20™ LoadingReferences:Prevenar 20™ (Pneumococcal 20-valent Conjugate Vaccine). Summary of Product Characteristics. Wyeth Pharmaceuticals LLC; 2024.Centers for Disease Control and Prevention. ACIP updates: recommendations for the use of 20-valent pneumococcal conjugate vaccine in children—United States, 2023. MMWR Morb Mortal Wkly Rep. 2023;72(39):1072. https://stacks.cdc.gov/view/cdc/133252Prevenar 13® (Pneumococcal 13-valent Conjugate Vaccine). Summary of Product Characteristics. Wyeth Pharmaceuticals LLC; 2014.Vaxneuvance™ (Pneumococcal 15-valent Conjugate Vaccine). Summary of Product Characteristics. Merck Sharp & Dohme Corp.; 2023.Hjuler T, Wohlfahrt J, Simonsen J, et al. Perinatal and crowding-related risk factors for invasive pneumococcal disease in infants and young children: a population-based case-control study. Clin Infect Dis. 2007;44(8):1051-1056.Chapman R, Sutton K, Dillon-Murphy D, et al. Ten year public health impact of 13-valent pneumococcal conjugate vaccination in infants: a modelling analysis. Vaccine. 2020;38(45):7138-7145.Prevenar® (Pneumococcal 7-valent Conjugate Vaccine). Summary of Product Characteristics. Wyeth Pharmaceuticals LLC; 2011.Local vaccine availability dates.
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